Introduction: This study aims to compare the effectiveness of mindfulness-based cognitive therapy and meta-cognitive therapy based on training on emotion regulation and anxiety sensitivity in elderly with precedent heart disease in Tehran city.
 Methods: This was an experimental study with pre-test & post-test and statistical population consisted of all elderly with precedent heart disease living in Tehran 2018, among whom 50 people with precedent heart disease were selected and randomly divided into two groups of equally 25 people. The first group received eight sessions of mindfulness-based cognitive therapy, and the second group was presented with eight sessions of meta-cognitive therapy based on training. Research tools were Emotion Regulation Questionnaire of Gross & John and Anxiety Sensitivity Index of Taylor & Coax (1998). Finally, data analysis was done by multivariate covariance.
 Results: The results showed significant effectiveness of independent variables (mindfulness-based cognitive therapy and meta-cognitive therapy based on training) on emotion regulation and anxiety sensitivity (p < 0.001). However, the results showed that metacognitive education had a more significant effect on anxiety fear control than mindful cognitive therapy.
Conclusion: Mindfulness-based cognitive therapy and meta-cognitive therapy based on training on emotion regulation and anxiety sensitivity had different effectiveness. So, experts should pay attention to this issue..