en عمومى General پژوهشي Research <div style="text-align: justify;"><strong>Introduction:</strong> Aging involves a decrease in&nbsp; physiological function, physical activity and nutrition that modulate body functions. The aim of this study was to evaluate the effect of a six week-swimming interval training with resveratrol consumption on apoptotic markers in the liver tissue of aged rat.<br> <strong>Methods:</strong> In this experimental study, thirty-two <a name="_Hlk69732539">20-month aged rats </a>weighing 350-370 g were divided into four groups of 8 rats including 1) sham, 2) training, 3) resveratrol and 4) training + resveratrol. For six weeks, groups 3 and 4 received 100 mg/kg of resveratrol supplementation dissolved in 1% methylcellulose daily by gavage, and groups 2 and 4 performed swimming training three times a week. One-way analysis of variance with Tukey&#39;s post- hoc test was used to analyze the data (p < 0.05).<br> <strong>Results:</strong> Bcl2 Gene expression levels in the resveratrol and the exercise + resveratrol groups were significantly higher than the sham and exercise groups (p < 0.05).&nbsp; Bax levels in the exercise + resveratrol group were lower than the resveratrol group, and the levels in the resveratrol group were higher than the sham group(p <0.05).also Bax/Bcl2 levels in the exercise + resveratrol group were significantly lower than the exercise group(p < 0.05).<br> <strong>Conclusion</strong>: It seems that swimming interval training with resveratrol consumption has beneficial effects on anti-apoptotic markers, however, the effect of swimming interval training on liver apoptosis in the aging is still unknown and more studies are needed in this field.<span dir="RTL"></span></div> Swimming Training, Resveratrol, Apoptosis, Liver, Aging 39 44 http://ehj.ssu.ac.ir/browse.php?a_code=A-10-291-1&slc_lang=en&sid=1 Maryam Mehboudi mehboodimaryam@yahoo.com No Department of Physical Education and Sport Sciences, Aliabad Katoul Branch, Islamic Azad University, Aliabad Katoul, Iran Habib Asgharpour habibasgharpour@gmail.com https://orcid.org/0000-0002-4116-981X Yes Department of Physical Education and Sport Sciences, Aliabad Katoul Branch, Islamic Azad University, Aliabad Katoul, Iran Seyed Ali Hosseini No Department of Sport Physiology, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran Reza Rezaeeshirazi No Department of Physical Education and Sport Sciences, Aliabad Katoul Branch, Islamic Azad University, Aliabad Katoul, Iran