en تخصصي Special پژوهشي Research <p><span style="font-size:16px;"><span style="font-family:times new roman;"><strong>Introduction:</strong> Aging is associated with elevated levels of some proinflammatory factors and exercise is a non-invasive intervention to improve immune function among older adults .The aim of the study was to compare resistance training effects on interlukine-6 (IL-6) and high-sensitivity C-reactive protein (hs-CRP) levels in older-aged women.</span></span></p> <p></p> <p><span style="font-size:16px;"><span style="font-family:times new roman;"><strong>Methods:</strong> The study was quasi-experimental and forty healthy females were selected and randomly assigned to one of four groups: strength after endurance training (endurance + strength (E + S), n = 9), strength prior to endurance training (strength + endurance (S + E), n = 10), interval resistance-endurance training (Int, n = 12), and control (n = 9) groups. The training program was performed for eight weeks, three times per week. Human TNF-&alpha; and IL-6 sandwich ELISA Kit were used. Within-group differences were analyzed using a paired samples t-test and between-group differences were analyzed using one-way analysis of variance.</span></span></p> <p></p> <p><span style="font-size:16px;"><span style="font-family:times new roman;"><strong>Results:</strong> The intra-session order had not significantly influence on the adaptive response of waist-to-hip ratio (p = 0.55), IL-6 (p = 0.55) and hs-CRP (p = 0.55) throughout the study. However, significant differences were shown following combined training between the S + E, E + S and Int groups for Vo2 max (p = 0.029), body mass (p = 0.016) and BMI (p = 0.023) when comparing pre and posttests.</span></span></p> <p></p> <p><span style="font-size:16px;"><span style="font-family:times new roman;"><strong>Conclusion</strong>: This study confirmed that adaptations to a combination of endurance and resistance training appear to be independent of whether resistance training occurs prior to or following endurance training<strong><em>.</em></strong></span></span></p> Exercise, Inflammation, IL-6, hs-CRP, Aging 35 41 http://ehj.ssu.ac.ir/browse.php?a_code=A-10-1-27&slc_lang=en&sid=1 Zahra Mardanpour Shahrekordi No Department of Sport Sciences, School of Human Sciences, University of Shahrekord, Shahrekord, Iran Ebrahim Banitalebi banitalebi@lit.sku.ac.ir Yes Department of Sport Sciences, School of Human Sciences, University of Shahrekord, Shahrekord, Iran Mohammad Faramarzi No Department of Sport Sciences, School of Human Sciences, University of Shahrekord, Shahrekord, Iran