Volume 8, Issue 1 (June 2022)                   Elderly Health Journal 2022, 8(1): 36-42 | Back to browse issues page

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Fereidouni Valashejerdi Z, Abolghasemi S, Khalatbari J, Tarkhan M. Effectiveness of Cognitive Rehabilitation on Agitation, Apathy and Cognitive Function in Male Elders with Mild Cognitive Impairment. Elderly Health Journal. 2022; 8 (1) :36-42
URL: http://ehj.ssu.ac.ir/article-1-248-en.html
Department of Health Psychology, Faculty of Psychology, Tonekabon Branch, Islamic Azad University, Tonekabon, Iran , zfereidouni@yahoo.com
Abstract:   (141 Views)
Introduction: The elders need proper medical and psychiatric care and attention, so choosing a suitable therapeutic approach for their psychological care, especially in those with cognitive impairment, will be effective in improving psychological symptoms and their health. The present study aimed to investigate the effectiveness of cognitive rehabilitation on agitation, apathy and cognitive function.
Methods: This quasi-experimental study carried out among male elders with mild cognitive impairment (MCI) in Kahrizak Charity nursing home in Alborz province in 2020. A sample of 36 male elders with MCI was purposefully selected and randomly assigned to experimental (n = 18) and control (n = 18) groups. Data were collected through Cohen-Mansfield Agitation Inventory; Apathy Evaluation Scale and Montreal Cognitive Assessment-Basic. The intervention group received 8 sessions of 90 minutes, cognitive rehabilitation based on kelly and O'Sullivan's cognitive rehabilitation strategies and techniques.
Results: After controlling the mean scores of the pretest, a significant difference was observed in agitation (96.6 vs 101.9) apathy (30.02 vs 34.10) and cognitive function (19.60 vs 16.80) between experimental and control groups. This means that cognitive rehabilitation reduced agitation and apathy with effect sizes of 0.42 and 0.54 respectively and increased cognitive function with an effect size of 0.65.
Conclusion: Considering the effectiveness of cognitive rehabilitation in reducing agitation, apathy and increasing cognitive function of the participants, cognitive rehabilitation is suggested to improve individual functioning and interpersonal relationships in the elderly with MCI.

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Type of Study: Research | Subject: Special
Received: 2021/11/27 | Accepted: 2022/05/31 | Published: 2022/06/29

1. Alzheimer’s Association. Alzheimer's disease facts and figures. Alzheimer’s Dementia [Internet]. 2018 [Cited 2021 Oct 1]. Available from: https://www.alz.org/media/Documents/alzheimers-facts-and-figures.pdf
2. Sadock BJ, Sadock VA, Ruiz P. Kaplan & Sadockʹs synopsis of psychiatry behavioral sciences clinical psychiatry [Purafkari N, trans]. LWW; 2014.
3. Jean L, Bergeron MÈ, Thivierge S, Simard M. Cognitive intervention programs for individuals with mild cognitive impairment: Systematic review of the literature. The American Journal of Geriatric Psychiatry. 2010; 18(4): 281-96.
4. Simpson JR. DSM-5 and neurocognitive disorders. The Journal of the American Academy of Psychiatry and the Law. 2014; 42(2): 159-64.
5. Cherry K. Diagnostic and statistical manual of mental disorders. 5th edition; DSM-5-TR™. Washington, DC: American Psychiatric Association; 2022.
6. Duff K. Mild cognitive impairment and dementia: Definitions, diagnosis, and treatment. Archives of Clinical Neuropsychology. 2014; 29(7): 691–2.
7. Sachdev PS, Lipnicki DM, Kochan NA, Crawford JD, Thalamuthu A, Andrews G, et al. The prevalence of mild cognitive impairment in diverse geographical and ethno cultural regions: The COSMIC collaboration. PLoS One. 2015; 10(11): 1-19.
8. Flicker C, Ferris SH, Reisberg B. Mild cognitive impairment in the elderly: predictors of dementia. Neurology. 1991; 41(7): 1006-9.
9. Petersen RC, Smith GE, Waring SC, Ivnik RJ, Tangalos EG, Kokmen E. Mild cognitive impairment: Clinical characterization and outcome. Archives of Neurology. 1999; 56(1): 303-8.
10. Petersen RC. Mild cognitive impairment as a diagnostic entity. Journal of Internal Medicine. 2004; 256(3): 183-94.
11. Janelidze M, Botchorishvili N. Mild cognitive impairment. In: Dorszewska J, Kozubski W. Alzheimer’s disease-The 21st Century Challenge. Georgia: 2018. p. 91-107.
12. Gold CA, Budson AE. Memory loss in Alzheimer’s disease: implications for development of therapeutics. Expert Review Neurotherapeutics. 2008; 8(12): 1879-91.
13. Holtzer R, Tang MX, Devanand DP, Albert SM, Wegesin DJ, Marder K, et al. Psychopathological features in Alzheimer’s disease: Course and relationship with cognitive status. Journal of American Geriatrics Society. 2003; 51(7): 953–60.
14. Gomez-Soria L, Peralta-Marrupe P, Plo F. Cognitive stimulation program in mild cognitive impairment A randomized controlled trial. Dementia e Neuropsychologia. 2020; 14(2):110-7.
15. Rozzini L, Costardi D, Chilovi BV, Franzoni S, Trabucchi, M, Padovani, A. Efficacy of cognitive rehabilitation in patients with mild cognitive impairment treated with cholinesterase inhibitors. International Journal of Geriatric Psychiatry. 2007; 22(4): 356–60.
16. Kelly ME, Lawlor BA, Coen RF, Robertson IH, Brennan S. Cognitive rehabilitation for early stage Alzheimer’s disease; a pilot study with an Irish population. Irish Journal of Psychological Medicine. 2017; 36(2): 1–15.
17. Clare L, Bayer A, Burns A, Corbett A, Jones R, Knapp M, et al. Goal-oriented cognitive rehabilitation in early-stage dementia; study protocol for a multi-center single-blind randomized controlled trial (GREAT). Trials. 2013; 14(1): 1-16.
18. Giuli C, Papa R, Lattanzio F, Postacchini D. The effects of cognitive training for elderly; results from my mind project. Rejuvenation Research. 2016; 19(6): 485–94.
19. Zare M, Shayeghian Z, Birashk B, Afkham Ebrahimi A. Reliability, validity and factor analysis of cohen-mansfield agitation inventory (CMAI). Iranian Journal of Psychiatry and Clinical Psychology. 2012; 18(1): 67-73. [Persian]
20. Cohen-Mansfield J. Instruction Manual for the cohen-mansfield agitation inventory (CMAI) [Internet]. USA: Rockville; 1991 [cited 2021 Oct 10]. Available from: https://dementiaresearch.org.au/wp-content/uploads/2016/06/CMAI_Manual.pdf
21. Griffiths Aw, Albertyn ChP, Burnley NL, Creese B, Walwyn R, Holloway I, et al. Validation of the cohen-mansfield agitation inventory observational (CMAI-O) tool. International Psychogeriatrics. 2020; 32(1): 75-85
22. Marin RS. Apathy: a neuropsychiatric syndrome. The Journal of Neuropsychiatry and Clinical Neurosciences. 1991; 3(3): 243–54.
23. Umucu E, Wyman M, Lee B, Zuelsdorff M, Benton SF, Nystrom N, et al. Apathy in preclinical alzheimer’s disease: psychometric validation of the apathy evaluation scale. American Journal of Alzheimer’s Disease & Other Dementias. 2018; 34(1): 16-22.
24. Nasreddine ZS, Phillips NA, Bedirian V, Charbonneau S, Whitehead V, Collin I, et al. The Montreal cognitive assessment, MoCA: A brief screening tool for mild cognitive impairment. Journal of the American Geriatrics Society. 2005; 53(4): 695-9.
25. Saleh A, Alkholy R, Osama O, Sabry NA, Amer H, El-Jaafary S, et al. Validation of Montreal cognitive assessment-basic in a sample of elderly Egyptians with neurocognitive disorders. Aging and Mental Health. 2019; 23(5): 551-7.
26. Kelly ME, O’Sullivan M. Strategies and techniques for cognitive rehablitaion: Manual for healthcare professionals working with individuals with cognitive impairment [Internet]. Department of Environment; 2015 [cited 2021 Agu 12]. Available from: /alzheimer.ie/wp-content/uploads/2019/07/2015-Cognitive-Rehabilitation.pdf
27. Corrigan JD, Mysiw WJ. Agitation following traumatic head injury: equivocal evidence for a discrete stage of cognitive recovery. Archives of Physical Medicine and Rehabilitation. 1988; 69(7): 487-92.
28. Montoya-Murillo G, Ibarretxe-Bilbao N, Peña J, Ojeda N. Effects of cognitive rehabilitation on cognition, apathy, quality of life, and subjective complaints in the elderly: a randomized controlled trial. The American Journal of Geriatric Psychiatry. 2020; 28(5): 518-529.
29. Brodaty H, Burns K. Nonpharmacological management of apathy in dementia; a systematic review. The American Journal of Geriatric Psychiatry. 2012; 20(7): 549–564.
30. Skidmore ER, Whyte EM, Butters MA, Terhorst L, Reynolds CF. Strategy training during inpatient rehabilitation may prevent apathy symptoms after acute stroke. The Journal of Injury, Function, and Rehabilitation. 2015; 7(6): 562–570.
31. Skidmore ER, Dawson DR, Butters MA, Grattan ES, Juengst SB, Whyte EM, et al. strategy training shows promise for addressing disability in the first 6 months after stroke. Neurorehabilitation and Neural Repair. 2014; 29(7): 668–676.
32. Zare H, Siahjani L. The efficacy of cognitive rehabilitation on mental state and memory function of the elderly with mild Alzheimer's. Journal in Advances in Cognitive Sciences. 2018; 20(3):51-66.
33. Rahe J, Petrelli A, Kaesberg S, Fink GR, Kessler J, Kalbe E. Effects of cognitive training with additional physical activity compared to pure cognitive training in healthy older adults. Clinical Interventions in Aging. 2015; 10(1): 297–310.
34. Reijnders J, van Heugten C, van Boxtel M. Cognitive interventions in healthy older adults and people with mild cognitive impairment: a systematic review. Ageing Research Reviews. 2013; 12(1): 263–275.

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