Impact of Exercise on Fall and Its Consequences among Elderly People

Kushkestani, Mehdi; Parvani, Mohsen; Baradaran, Raheleh; Rezaei, Alireza; Pourhamzeh, Hamed

doi:10.18502/ehj.v9i1.13109

Volume 9, Issue 1 (June 2023) Elderly Health Journal 2023, 9(1): 44-54 | Back to browse issues page

‎ 10.18502/ehj.v9i1.13109

‎ 20.1001.1.24236179.2023.9.1.8.7

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Kushkestani M, Parvani M, Baradaran R, Rezaei A, Pourhamzeh H. Impact of Exercise on Fall and Its Consequences among Elderly People. Elderly Health Journal 2023; 9 (1) :44-54
URL: http://ehj.ssu.ac.ir/article-1-270-en.html

Impact of Exercise on Fall and Its Consequences among Elderly People

Mehdi Kushkestani

, Mohsen Parvani ^*

, Raheleh Baradaran

, Alireza Rezaei

, Hamed Pourhamzeh

Department of Physical Activity and Health, Faculty of Sport Sciences and Physical Education, University of Coimbra, Coimbra, Portugal , mparva2020@gmail.com

Abstract: (507 Views)

Falls are a threat to the health of older adults and can reduce their ability to remain independent. Furthermore, fall is known as one of the geriatric syndromes and is more common in older people and about 20 to 40 percent of older people have reported a history of falling per year. It should be noted that fall or fear of falling causes immobility in the elderly and immobility is linked with various non-communicable diseases, geriatric syndromes development, and mortality in the long term. As a result, finding a cost-effective, safe, and proper approach to prevent, control, and even treat of falls is absolutely crucial. Regarding the exercise benefits in all ages especially in the elderly, we supposed that various types of exercise such as aerobic, balance, and resistance training with different intensities have variant advantages in these subjects. Therefore, in this review study, we investigated the charter of different types of exercise in preventing and controlling fall based on recent evidence, providing involved mechanisms, as well as the effects of exercises on fall-related risk factors.

Keywords: Aerobic Exercise, Exercise Therapy, Sarcopenia, Elderly, Health

Full-Text [PDF 388 kb] (315 Downloads) | | Full-Text (HTML) (532 Views)

Type of Study: Research | Subject: General
Received: 2022/08/22 | Accepted: 2023/06/25 | Published: 2023/06/20

References

1. Alqahtani BA, Alshehri MM, Hoover JC, Alenazi AM. Prevalence of falls among older adults in the Gulf Cooperation Council countries: a systematic review and meta-analysis. Archives of Gerontology and Geriatrics. 2019; 83: 169–74.

2. Sharif SI, Al-Harbi AB, Al-Shihabi AM, Al-Daour DS, Sharif RS. Falls in the elderly: assessment of prevalence and risk factors. Pharmacy Practice (Granada). 2018; 16(3): 1-7.

3. Stanaway FF, Cumming RG, Naganathan V, Blyth FM, Handelsman DJ, Le Couteur DG, et al. Ethnicity and falls in older men: low rate of falls in Italian-born men in Australia. Age and Ageing. 2011; 40(5): 595–601.

4. Severo IM, Almeida M de A, Kuchenbecker R, Vieira DFVB, Weschenfelder ME, Pinto LRC, et al. Risk factors for falls in hospitalized adult patients: an integrative review. Revista da Escola de Enfermagem da USP. 2014; 48(3):540–54.

5. Nazrun AS, Tzar MN, Mokhtar SA, Mohamed IN. A systematic review of the outcomes of osteoporotic fracture patients after hospital discharge: morbidity, subsequent fractures, and mortality. Therapeutics and Clinical Risk Management. 2014; 10: 937-48.

6. Kelsey JL, Berry SD, Procter-Gray E, Quach L, Nguyen USD, Li W, et al. Indoor and outdoor falls in older adults are different: the maintenance of balance, independent living, intellect, and Zest in the Elderly of Boston Study. Journal of the American Geriatrics Society. 2010; 58(11): 2135–41.

7. Bergen G, Stevens MR, Burns ER. Falls and fall injuries among adults aged ≥ 65 years—United States, 2014. Morbidity and Mortality Weekly Report. 2016; 65(37): 993–8.

8. Abreu DR de OM, Azevedo RC de S, Silva AMC da, Reiners AAO, Abreu HCA. Factors associated with recurrent falls in a cohort of older adults. Ciencia & Saude Coletiva. 2016; 21: 3439–46.

9. Unguryanu TN, Grjibovski AM, Trovik TA, Ytterstad B, Kudryavtsev AV. Weather conditions and outdoor fall injuries in Northwestern Russia. International Journal of Environmental Research and Public health. 2020; 17(17): 1-16.

10. Luk JK, Chan TY, Chan DK. Falls prevention in the elderly: translating evidence into practice. Hong Kong Medical Journal. 2015; 21(2): 165–71.

11. Demanze Laurence B, Michel L. The fall in older adults: physical and cognitive problems. Current Aging Science. 2017; 10(3): 185–200.

12. Liu W, Yang LH, Kong XC, An LK, Wang R. Meta-analysis of osteoporosis: fracture risks, medication and treatment. Minerva Medica. 2015; 106(4): 203–14.

13. Ehlinger M, Favreau H, Eichler D, Adam P, Bonnomet F. Early mechanical complications following fixation of proximal femur fractures: From prevention to treatment. Orthopaedics & Traumatology: Surgery & Research. 2020; 106(1): 79–87.

14. Pi HY, Hu MM, Zhang J, Peng PP, Nie D. Circumstances of falls and fall-related injuries among frail elderly under home care in China. International Journal of Nursing Sciences. 2015; 2(3): 237–42.

15. Kushkestani M, Nosrani SE, Parvani M, Rezaei S. The relationship between the level of physical activity and dementia in elderly residents of nursing homes in Tehran. Biomedical Journal of Scientific & Technical Research. 2020; 29(3):22437–43.

16. Kushkestani M, Parvani M, Bathaeezadeh SY, Pour Nosrani SE. The evaluation of differences on geriatric syndromes between active and sedentary elderly. Journal of Sports Science. 2020; 8: 56–66.

17. Kushkestani M, Parvani M, Nosrani SE, Rezaei S. The physical activity and fall risk among Iranian older male adults. The Open Nursing Journal. 2020; 14(1): 159-67.

18. Kersten S. Physiological regulation of lipoprotein lipase. Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids. 2014; 1841(7): 919–33.

19. Johnson VE, Stewart W, Smith DH. Traumatic brain injury and amyloid-β pathology: a link to Alzheimer’s disease?. Nature Reviews Neuroscience. 2010; 11(5): 361–70.

20. Boltz M, Resnick B, Capezuti E, Shuluk J. Activity restriction vs. self-direction: hospitalised older adults’ response to fear of falling. International Journal of Older People Nursing. 2014; 9(1): 44–53.

21. Hadjistavropoulos T, Delbaere K, Fitzgerald TD. Reconceptualizing the role of fear of falling and balance confidence in fall risk. Journal of Aging and Health. 2011; 23(1): 3–23.

22. Hull SL, Kneebone II, Farquharson L. Anxiety, depression, and fall-related psychological concerns in community-dwelling older people. The American Journal of Geriatric Psychiatry. 2013; 21(12): 1287–91.

23. Meyer M, Constancias F, Vogel T, Kaltenbach G, Schmitt E. Gait disorder among elderly people, psychomotor disadaptation syndrome: post-fall syndrome, risk factors and follow-up–a cohort study of 70 patients. Gerontology. 2021; 67(1): 17–24.

24. Heinrich S, Rapp K, Rissmann U, Becker C, König HH. Cost of falls in old age: a systematic review. Osteoporosis International. 2010; 21: 891–902.

25. Florence CS, Bergen G, Atherly A, Burns E, Stevens J, Drake C. Medical costs of fatal and nonfatal falls in older adults. Journal of the American Geriatrics Society. 2018; 66(4): 693–8.

26. Haddad YK, Bergen G, Florence C. Estimating the economic burden related to older adult falls by state. Journal of Public Health Management and Practice: JPHMP. 2019; 25(2): 17-24.

27. de Almeida ST, Soldera CLC, de Carli GA, Gomes I, de Lima Resende T. Analysis of extrinsic and intrinsic factors that predispose elderly individuals to fall. Revista da Associação Médica Brasileira (English Edition). 2012; 58(4): 427–33.

28. Kushkestani M, Moghadassi M, Parvani M, Nosrani SE, Rezaei S. Physical activity as a preventive factor to aging-related physical dysfunction in Iranian community-dwelling elderly. Journal of Aging Science. 2020; 8(4): 1-7.

29. Kushkestan M, Nosrani SE, Parvani M, Moghadassi M, Rezaei S, Tartibian B, et al. Active lifestyle prevent sarcopenia in older men. Lifestyle Medicine Research & Reviews. 2023; 1(1): 35-40.

30. Collins KH, Herzog W, MacDonald GZ, Reimer RA, Rios JL, Smith IC, et al. Obesity, metabolic syndrome, and musculoskeletal disease: common inflammatory pathways suggest a central role for loss of muscle integrity. Frontiers in Physiology. 2018; 9: 1-25.

31. Baylis D, Bartlett DB, Patel HP, Roberts HC. Understanding how we age: insights into inflammaging. Longevity & Health Span. 2013; 2(1): 1-8.

32. Kob R, Bollheimer LC, Bertsch T, Fellner C, Djukic M, Sieber CC, et al. Sarcopenic obesity: molecular clues to a better understanding of its pathogenesis? Biogerontology. 2015; 16(1): 15–29.

33. Migliaccio S, Greco EA, Wannenes F, Donini LM, Lenzi A. Adipose, bone and muscle tissues as new endocrine organs: role of reciprocal regulation for osteoporosis and obesity development. Hormone Molecular Biology and Clinical Investigation. 2014; 17(1): 39–51.

34. Landi F, Liperoti R, Russo A, Giovannini S, Tosato M, Capoluongo E, et al. Sarcopenia as a risk factor for falls in elderly individuals: results from the ilSIRENTE study. Clinical Nutrition. 2012; 31(5): 652–8.

35. Kushkestani M, Parvani M, Ghafari M, Avazpoor Z. The role of exercise and physical activity on aging-related diseases and geriatric syndromes. SPORT TK-Revista EuroAmericana de Ciencias del Deporte. 2022; 11:1-32.

36. Malafarina V, Úriz-Otano F, Iniesta R, Gil-Guerrero L. Sarcopenia in the elderly: diagnosis, physiopathology and treatment. Maturitas. 2012; 71(2): 109–14.

37. Quigley PA, Bulat T, Schulz B, Friedman Y, Hart-Hughes S, Richardson JK, et al. Exercise interventions, gait, and balance in older subjects with distal symmetric polyneuropathy: a three-group randomized clinical trial. American Journal of Physical Medicine & Rehabilitation. 2014; 93(1): 1–16.

38. Yip JL, Khawaja AP, Broadway D, Luben R, Hayat S, Dalzell N, et al. Visual acuity, self-reported vision and falls in the EPIC-Norfolk Eye study. British Journal of Ophthalmology. 2014; 98(3): 377–82.

39. Sibley KM, Voth J, Munce SE, Straus SE, Jaglal SB. Chronic disease and falls in community-dwelling Canadians over 65 years old: a population-based study exploring associations with number and pattern of chronic conditions. BMC Geriatrics. 2014; 14(1):1–11.

40. Hung WW, Ross JS, Boockvar KS, Siu AL. Recent trends in chronic disease, impairment and disability among older adults in the United States. BMC Geriatrics. 2011; 11(1): 1–12.

41. Rossini M, Viapiana O, Vitiello M, Malavolta N, La Montagna G, Bongi SM, et al. Prevalence and incidence of osteoporotic fractures in patients on long-term glucocorticoid treatment for rheumatic diseases: the Glucocorticoid Induced OsTeoporosis TOol (GIOTTO) study. Reumatismo. 2017; 69(1): 30–9.

42. Berlie HD, Garwood CL. Diabetes medications related to an increased risk of falls and fall-related morbidity in the elderly. The Annals of Pharmacotherapy. 2010; 44(4): 712–7.

43. Hewston P, Deshpande N. Falls and balance impairments in older adults with type 2 diabetes: thinking beyond diabetic peripheral neuropathy. Canadian Journal of Diabetes. 2016; 40(1): 6–9.

44. Rothenbacher D, Klenk J, Denkinger MD, Herbolsheimer F, Nikolaus T, Peter R, et al. Prospective evaluation of renal function, serum vitamin D level, and risk of fall and fracture in community-dwelling elderly subjects. Osteoporosis International. 2014; 25(3): 923–32.

45. Sanders KM, Scott D, Ebeling PR. Vitamin D deficiency and its role in muscle-bone interactions in the elderly. Current Osteoporosis Reports. 2014; 12(1): 74–81.

46. Milos V, Bondesson A, Magnusson M, Jakobsson U, Westerlund T, Midlöv P. Fall risk-increasing drugs and falls: a cross-sectional study among elderly patients in primary care. BMC Geriatrics. 2014; 14(1): 1–7.

47. Campanelli CM. American Geriatrics Society updated beers criteria for potentially inappropriate medication use in older adults. Journal of the American Geriatrics Society. 2012; 60(4): 616-31.

48. Stone KL, Blackwell TL, Ancoli-Israel S, Cauley JA, Redline S, Marshall LM, et al. Sleep disturbances and risk of falls in older community-dwelling men: the outcomes of Sleep Disorders in Older Men (MrOS Sleep) Study. Journal of the American Geriatrics Society. 2014; 62(2): 299–305.

49. Zhang Y, Cifuentes M, Gao X, Amaral G, Tucker KL. Age-and gender-specific associations between insomnia and falls in Boston Puerto Rican adults. Quality of Life Research. 2017; 26(1): 25–34.

50. Simoncini M, Gatti A, Quirico PE, Balla S, Capellero B, Obialero R, et al. Acupressure in insomnia and other sleep disorders in elderly institutionalized patients suffering from Alzheimer’s disease. Aging Clinical and Experimental Research. 2015; 27(1): 37–42.

51. Ang GC, Low SL, How CH. Approach to falls among the elderly in the community. Singapore Medical Journal. 2020; 61(3): 116-21.

52. Zhang L, Ding Z, Qiu L, Li A. Falls and risk factors of falls for urban and rural community-dwelling older adults in China. BMC Geriatrics. 2019; 19(1): 1–17.

53. Jin J. Prevention of falls in older adults. JAMA Patient Page. 2018; 319(16): 1734.

54. Kushkestani M, Parvani M, Ebrahimpour Nosrani SEP, Bathaeezadeh SY. The relationship between body composition with blood pressure and sleep quality in male dormitory student at Allameh Tabataba’i University. New Approaches in Exercise Physiology. 2022; 4(7): 91–106.

55. Kushkestani M, Parvani M, Nosrani SE, Bathaeezadeh SY. The relationship between drug use, sleep quality and quality of life in dormitory students at Allameh Tabataba’i University, Iran. Population Medicine. 2020; 2: 1-7.

56. Kushkestani M, Parvani M, Maria Teixeira A. physical activity is a preventive factor against sars-cov-2 in healthy subjects (Possible Cellular and Molecular Mechanisms). Biomedical Journal of Scientific & Technical Research. 2020; 29(3): 22429–36.

57. Kushkestani M, Parvani M, Kazemzadeh Y. SARS-COV-2 in type 2 diabetic patients: Possible roles of exercise training as a medicine. Current Diabetes Reviews. 2022; 18(7): 1–7.

58. Kushkestani M, Parvani M, Nosrani SE, Rezaei S. The relationship between Anthropometric indices and lipid profiles in-officeemployees. Journal of Sports Science. 2020; 8: 76–82.

59. Kushkestani M, Parvani M, Moghadassi M, Kazemzadeh Y, Moradi K. Impact of hypertension and physical fitness on SARS-COV-2 and related consequences.(Possible mechanisms with focusing on ACE2). Caspian Journal of Internal Medicine. 2022; 13(3): 148-54.

60. Kushkestani M, Parvani M, Moghadassi M, Baradaran R. The effect of six-week high-intensity interval training on muscle expression of FTO and PPAR-γ in obese diabetic rats. Iranian Journal of Health Sciences. 2022; 10(2): 29-39.

61. Tartibian B, Kushkestani M, Ebrahimpour Nosrani SE. The effect of 12-week endurance training on lipid profiles and fat percentage of overweight girls. New Approaches in Exercise Physiology. 2019; 1(1): 189-200.

62. Osoba MY, Rao AK, Agrawal SK, Lalwani AK. Balance and gait in the elderly: A contemporary review. Laryngoscope Investigative Otolaryngology. 2019; 4(1): 143–53.

63. Ghasemi P, Nazem F, Etemadifar M, Parvani M. Comparing the effects of selected TRX and Pilates training on balance parameters, fatigue index, and quality of life in female patients of multiple sclerosis. New Approaches in Exercise Physiology. 2022; 4(8).

64. Phu S, Vogrin S, Al Saedi A, Duque G. Balance training using virtual reality improves balance and physical performance in older adults at high risk of falls. Clinical Interventions in Aging. 2019; 14: 1567-77.

65. Leiros-Rodríguez R, García-Soidan JL. Balance training in elderly women using public parks. Journal of Women & Aging. 2014; 26(3): 207–18.

66. Zhao Y, Chung PK, Tong TK. Effectiveness of a balance-focused exercise program for enhancing functional fitness of older adults at risk of falling: a randomised controlled trial. Geriatric Nursing. 2017; 38(6): 491–7.

67. Ogaya S, Ikezoe T, Soda N, Ichihashi N. Effects of balance training using wobble boards in the elderly. The Journal of Strength & Conditioning Research. 2011; 25(9): 2616–22.

68. Taube W. Neurophysiological adaptations in response to balance training. German Journal of Sports Medicine/Deutsche Zeitschrift fur Sportmedizin. 2012; 63(9): 273-7.

69. Vitorino LM, Teixeira CAB, Boas ELV, Pereira RL, Santos NO dos, Rozendo CA. Fear of falling in older adults living at home: associated factors. Revista da Escola de Enfermagem da USP. 2017; 51: 1-11.

70. Cadore EL, Rodríguez-Mañas L, Sinclair A, Izquierdo M. Effects of different exercise interventions on risk of falls, gait ability, and balance in physically frail older adults: a systematic review. Rejuvenation Research. 2013; 16(2): 105–14.

71. Liguori G, Medicine AC of S. ACSM’s guidelines for exercise testing and prescription. 11th ed. Lippincott Williams & Wilkins; 2020.

72. Bouaziz W, Vogel T, Schmitt E, Kaltenbach G, Geny B, Lang PO. Health benefits of aerobic training programs in adults aged 70 and over: a systematic review. Archives of Gerontology and Geriatrics. 2017; 69: 110–27.

73. Lakatta EG. So! What’s aging? Is cardiovascular aging a disease? Journal of Molecular and Cellular Cardiology. 2015; 83: 1–13.

74. Lee PG, Jackson EA, Richardson CR. Exercise prescriptions in older adults. American Family Physician. 2017; 95(7): 425–32.

75. Sousa N, Mendes R, Silva A, Oliveira J. Combined exercise is more effective than aerobic exercise in the improvement of fall risk factors: a randomized controlled trial in community-dwelling older men. Clinical Rehabilitation. 2017; 31(4): 478–86.

76. Levin O, Netz Y, Ziv G. The beneficial effects of different types of exercise interventions on motor and cognitive functions in older age: a systematic review. European Review of Aging and Physical Activity. 2017; 14(1): 1–23.

77. Pedersen BK, Saltin B. Exercise as medicine–evidence for prescribing exercise as therapy in 26 different chronic diseases. Scandinavian Journal of Medicine & Science in Sports. 2015; 25: 1–72.

78. Ruas JL, White JP, Rao RR, Kleiner S, Brannan KT, Harrison BC, et al. A PGC-1α isoform induced by resistance training regulates skeletal muscle hypertrophy. Cell. 2012; 151(6): 1319–31.

79. Johnson ML, Robinson MM, Nair KS. Skeletal muscle aging and the mitochondrion. Trends in Endocrinology & Metabolism. 2013; 24(5): 247–56.

80. Ziaaldini MM, Marzetti E, Picca A, Murlasits Z. Biochemical pathways of sarcopenia and their modulation by physical exercise: a narrative review. Frontiers in Medicine. 2017; 4: 1-8.

81. Broskey NT, Greggio C, Boss A, Boutant M, Dwyer A, Schlueter L, et al. Skeletal muscle mitochondria in the elderly: effects of physical fitness and exercise training. The Journal of Clinical Endocrinology & Metabolism. 2014; 99(5): 1852–61.

82. Alghadir AH, Aly FA, Gabr SA. Effect of moderate aerobic training on bone metabolism indices among adult humans. Pakistan Journal of Medical Sciences. 2014; 30(4): 840-4.

83. Armamento-Villareal R, Aguirre L, Waters DL, Napoli N, Qualls C, Villareal DT. Effect of aerobic or resistance exercise, or both, on bone mineral density and bone metabolism in obese older adults while dieting: a randomized controlled trial. Journal of Bone and Mineral Research. 2020; 35(3): 430–9.

84. Fragala MS, Cadore EL, Dorgo S, Izquierdo M, Kraemer WJ, Peterson MD, et al. Resistance training for older adults: position statement from the national strength and conditioning association. The Journal of Strength & Conditioning Research. 2019; 33(8): 2019-52.

85. Lopez P, Pinto RS, Radaelli R, Rech A, Grazioli R, Izquierdo M, et al. Benefits of resistance training in physically frail elderly: a systematic review. Aging Clinical and Experimental Research. 2018; 30(8): 889–99.

86. Papa EV, Dong X, Hassan M. Resistance training for activity limitations in older adults with skeletal muscle function deficits: a systematic review. Clinical Interventions in Aging. 2017; 12: 955-61.

87. Conlon JA, Newton RU, Tufano JJ, Peñailillo LE, Banyard HG, Hopper AJ, et al. The efficacy of periodised resistance training on neuromuscular adaptation in older adults. European Journal of Applied Physiology. 2017; 117(6): 1181–94.

88. Beck BR, Daly RM, Singh MAF, Taaffe DR. Exercise and Sports Science Australia (ESSA) position statement on exercise prescription for the prevention and management of osteoporosis. Journal of Science and Medicine in Sport. 2017; 20(5): 438–45.

89. Atherton PJ, Smith K. Muscle protein synthesis in response to nutrition and exercise. The Journal of Physiology. 2012; 590(5): 1049–57.

90. Schiaffino S, Dyar KA, Ciciliot S, Blaauw B, Sandri M. Mechanisms regulating skeletal muscle growth and atrophy. The FEBS Journal. 2013; 280(17): 4294–314.

91. Jacobs BL, You JS, Frey JW, Goodman CA, Gundermann DM, Hornberger TA. Eccentric contractions increase the phosphorylation of tuberous sclerosis complex-2 (TSC2) and alter the targeting of TSC2 and the mechanistic target of rapamycin to the lysosome. The Journal of Physiology. 2013; 591(18): 4611–20.

92. Gumucio JP, Mendias CL. Atrogin-1, MuRF-1, and sarcopenia. Endocrine. 2013; 43(1): 12–21.

93. Luo L, Lu AM, Wang Y, Hong A, Chen Y, Hu J, et al. Chronic resistance training activates autophagy and reduces apoptosis of muscle cells by modulating IGF-1 and its receptors, Akt/mTOR and Akt/FOXO3a signaling in aged rats. Experimental Gerontology. 2013; 48(4): 427–36.

94. Hong AR, Kim SW. Effects of resistance exercise on bone health. Endocrinology and Metabolism. 2018; 33(4): 435-44.

95. Galea GL, Lanyon LE, Price JS. Sclerostin’s role in bone’s adaptive response to mechanical loading. Bone. 2017; 96: 38–44.

96. Kukuljan S, Nowson CA, Sanders KM, Nicholson GC, Seibel MJ, Salmon J, et al. Independent and combined effects of calcium-vitamin D3 and exercise on bone structure and strength in older men: an 18-month factorial design randomized controlled trial. The Journal of Clinical Endocrinology & Metabolism. 2011; 96(4): 955–63.

97. Kovacevic A, Mavros Y, Heisz JJ, Singh MAF. The effect of resistance exercise on sleep: a systematic review of randomized controlled trials. Sleep Medicine Reviews. 2018; 39: 52–68.

98. Miller DJ, Sargent C, Roach GD, Scanlan AT, Vincent GE, Lastella M. Moderate-intensity exercise performed in the evening does not impair sleep in healthy males. European Journal of Sport Science. 2020; 20(1): 80–9.